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[2H4]-阿瑞吡坦

Aprepitant-d4

CAS: 1133387-60-6

Molecular Formula: C23H17D4F7N4O3

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[2H4]-阿瑞吡坦 - Names and Identifiers

Name Aprepitant-d4
Synonyms Aprepitant-d4
[2H4]-Aprepitant
[2H4]-APREPITANT
5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl-2,3,5,6-d4)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
CAS 1133387-60-6

[2H4]-阿瑞吡坦 - Physico-chemical Properties

Molecular FormulaC23H17D4F7N4O3
Molar Mass538.451309512
Melting Point242-244°C
Solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
AppearanceSolid
ColorWhite to Off-White
Storage Condition-20°C Freezer

[2H4]-阿瑞吡坦 - Introduction

Aprepitant-d4(Aprepitant-d4) is a chemical substance in which several hydrogen atoms in its chemical structure are replaced by heavy hydrogen (D). It is an isotope-labeled compound of Aprepitant.

The Aprepitant-d4 is mainly used to study drug metabolism, pharmacokinetics and drug interactions. By using Aprepitant-d4, the metabolic pathway and rate of a drug in the body can be tracked to better understand its mechanism of action.

The preparation method of the Aprepitant-d4 includes using a chemical reaction to replace the hydrogen atoms in Arry with heavy hydrogen atoms. The deuterating reagent is usually reacted with Arry under suitable reaction conditions to generate Aprepitant-d4.

For safety information, Aprepitant-d4 toxicity, side effects, and safety are similar to ARI itself. However, because it is an isotopically labeled compound, its availability as a drug is low, and it is mainly used for scientific research. Follow laboratory safety regulations, avoid direct contact and ingestion, and properly store and dispose of waste. If you need to use Aprepitant-d4, it is recommended to consult relevant experts or institutions to ensure safe and compliant use.
Last Update:2024-04-09 20:02:46
[2H4]-阿瑞吡坦
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CAS: 1133387-60-6
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MedChemExpress (MCE)
Spot supply
Product Name: Aprepitant-d4 Visit Supplier Webpage Request for quotation
CAS: 1133387-60-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Aprepitant-d4 Visit Supplier Webpage Request for quotation
CAS: 1133387-60-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Aprepitant-d4 Visit Supplier Webpage Request for quotation
CAS: 1133387-60-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
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